Cefmetazole sodium

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Cefmetazole sodium (Sodium cefmetazole) 是一种半合成的头孢霉素类抗生素 (antibiotic)，具有广谱抗菌活性，包括革兰氏阳性菌、革兰氏阴性菌和厌氧菌。Cefmetazole sodium 与青霉素结合蛋白 (PBPs) 结合，干扰细菌细胞壁的生物合成。Cefmetazole sodium 用于妇科、腹腔、泌尿道、呼吸道、皮肤和软组织感染的研究。

Cefmetazole sodium is a semisynthetic cephamycin antibiotic. Target: Antibacterial Cefmetazole sodium has a broad spectrum of activity comparable to that of the second-generation cephalosporins, covering gram-positive, gram-negative, and anaerobic bacteria.(In Vitro):Cefmetazole sodium (Sodium cefmetazole) has antibiotic affinity to?S. aureus?with a MIC value of 1.0 mg/L and has affinity for PBP1, PBP2 and PBP3 with IC50?values of ≤0.3, 0.109 and 0.494 mg/L.(In Vivo):Cefmetazole sodium (Sodium cefmetazole) (100 mg/kg; i.h.; twice a day, for 7 days; male ICR mice) alters gut bacterial flora.

Cefmetazole sodium (Sodium cefmetazole) has antibiotic affinity to S. aureus with a MIC value of 1.0 mg/L and has affinity for PBP1, PBP2 and PBP3 with IC50 values of ≤0.3, 0.109 and 0.494 mg/L.

Cefmetazole sodium (Sodium cefmetazole) (100 mg/kg; i.h.; twice a day, for 7 days; male ICR mice) alters gut bacterial flora. Animal Model:Male ICR mice Dosage:100 mg/kg Administration:Subcutaneous injection; twice a day, for 7 days Result:Reduced Peyer's patch (PP) lymphocyte cell numbers while decreased bacterial numbers in the small intestine.

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Others

Other Targets

Others

Infection

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56796-39-5

493.52

C15H16N7NaO5S3

>98% (HPLC)

DMSO: 39mg/mL

CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)CSCC#N)OC)SC2)C(=O)[O-].[Na+]

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(-20℃)

With Ice Pack

≥ 2 years